There is no commercial air service to Marfa. The slogan for VisitMarfa is - Tough to Get Here. Tougher to Explain. But Once You Get Here, You Get It. - and we certainly believe that to be true. "Nearby" airports include:
Southwest Airlines also offers connections to Midland and El Paso from both Houston Hobby Airport (HOU) and Dallas Love Field (DAL).
Marfa and the Big Bend area are in one of the most beautiful places on Earth. It is important to remember, however, that it is still the high desert and can be inhospitable. The area around Marfa is one of the most remote in the lower 48 states.
While driving expect to not have any cellular service between major towns. Distances well over 100 miles between gas stations are not uncommon and many of those stations close early. Please ensure you maintain a full tank of gas and have water on hand before leaving on any drives. In the event you have car trouble it might be a long time before you see a passerby depending on the road.
Visit Big Bend! provides some great safety tips here.